NATURE NEUROSCIENCE | BRIEF COMMUNICATION
2013 Dec;16(12):1731-3. doi: 10.1038/nn.3573. Epub 2013 Nov 10.
Independent hypothalamic circuits for social and predator fear.
The neural circuits mediating fear to naturalistic threats are poorly understood. We found that functionally independent populations of neurons in the ventromedial hypothalamus (VMH), a region that has been implicated in feeding, sex and aggression, are essential for predator and social fear in mice. Our results establish a critical role for VMH in fear and have implications for selective intervention in pathological fear in humans.